In modern conditions: with the current ecology, not always constant stress, procreation has become a real problem for many families. Today, most babies are born only thanks to medical support. However, any treatment should be started and completed correctly.

The mechanism of action of Duphaston

The main active ingredient of the drug is the hormone progesterone, which can be translated from Latin as "an assistant or conductor of pregnancy." This hormone is produced in the female ovaries. Inflammatory processes and various diseases disrupt its sufficient production, which leads to reproductive dysfunction and.

In such cases, there is a need for its artificial replenishment. For this purpose, the drug Duphaston was developed by people and tested over the years. This synthetic hormone has a positive effect on the walls of the uterus, promotes attachment of the fetal egg to them. With a lack of progesterone, spontaneous miscarriages occur, or pregnancy does not occur at all.

Progesterone plays an equally important role in the process of lactation. With its help, additional lobules and passages are formed in the mammary glands of a woman. It also promotes the production of the hormone prolactin, which is necessary for colostrum.

Without affecting the functions of the future mother's liver, progestogens increase the reserves of glucose in the woman's body, providing the fetus with the necessary nutrition. It is the lack of glucose that explains drowsiness, cravings for sweets and increased appetite in women in the first trimesters of pregnancy.

After the twentieth week, the full production of progesterone is provided by the placenta, and the need for maintenance therapy is lost. But until then, taking Duphaston is a prerequisite for many pregnant women.

When is this drug prescribed

As a rule, Duphaston is prescribed at the stage of pregnancy planning, or in the first trimesters. It has been empirically proven that women taking this drug are less likely to suffer from bouts of nausea, uterine hypertension and other complications while waiting for the baby.

The main indications for the use of Duphaston are:

• luteal (progesterone) deficiency
• habitual or threatened miscarriage
• uterine bleeding and PMS with increased tension
• dysmenorrhea (irregular menstrual cycle) and amenorrhea (absence of menstruation for a long time)
• female infertility

In a word, the drug is quite in demand, but you should not consider it a panacea for all female diseases and use it without a doctor's prescription. Hormones are a delicate matter, requiring a competent approach and careful dosing. Here from benefit to harm and danger is only one step.

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In modern gynecology, Duphaston is loved and sometimes used unnecessarily, so to speak, "just in case." This fact can be called medical incompetence and even negligence.

Unreasonable and uncontrolled use of the drug can lead to a violation of the hormonal background, which will have to be restored for a long time and painstakingly.

Any intervention in the natural processes laid down by nature itself dulls and inhibits the usual functions of the body. Support is needed only in certain situations, when the fact of insufficiency is diagnosed and proven.

Contraindications

The female body is very fragile and vulnerable, especially during pregnancy. Any impact on it can have the most unpredictable consequences. Each medication has contraindications for use, and Duphaston is no exception.

Contraindications to the use of Duphaston:

• individual intolerance
• allergic reactions to the components of the drug
• lactase deficiency (inability to digest milk sugar)
• malabsorption syndrome (when some nutrients are not absorbed by the intestines, but are immediately excreted from the body)
• lactation period
• and reproductive organs

Drugs such as Phenobarbital and Rifampicin can reduce the effectiveness of Duphaston. This fact should be taken into account when combining these drugs.

An additional and important point: contrary to many opinions, Duphaston has a weak contraceptive effect. The excess of progesterone accumulated over time contributes to the inhibition of the pituitary gland and the gradual cessation of ovulation. This is another argument for maximalists.

Every expectant mother desperately wants to help her body and future baby. However, the sense of proportion and the recommendations of a professional doctor should not be overlooked, especially when it comes to taking medication.

Side effects

Negative effects on the female body are observed quite rarely, they can manifest themselves in the form of:

• migraine headaches
• peripheral edema
• minor liver dysfunction
• hemolytic anemia (destruction of red blood cells)

Cases of drug overdose have not been observed in medical practice, but in these situations, gastric lavage and activated charcoal are recommended. Judging by the reviews of patients taking this drug, diarrhea, nausea, pain in the lower abdomen and a noticeable weight gain may appear as side effects.

When caused by luteal insufficiency, it is necessary to take one tablet of Duphaston from the fourteenth to the twenty-fifth day of the menstrual cycle. Habitual miscarriage is an indication for the use of the drug twice a day for ten mg. In case of a threat of spontaneous abortion, four tablets should be taken once, then one every eight hours until complete relief.

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Duphaston's analogues are: Utrozhistan, Prajisan, Norkolut. You can replace the drug with them after consultation with your doctor. The possibility of replacement will depend on the condition, clinical picture and diagnosis of a particular patient.

Negative effects of the drug on the fetus were not recorded. The main condition for the development and growth of the embryo is the appropriate basal temperature and the necessary nutrients. Duphaston successfully raises and maintains this temperature at the desired level, with its significant and prolonged decrease, the fetus dies, a “frozen or frozen pregnancy” occurs.

The use of the drug in excess of the indicated dose and for an unreasonably long time can lead to excessive accretion of the placenta and postpartum complications. Within thirty minutes after delivery, the placenta flakes off and is expelled from the uterus. An excess of progesterone can disrupt this natural process, which threatens the woman in labor with a “manual separation” of the placenta or curettage of placental residues.

The scheme of cancellation of the course of treatment

So, not every woman needs artificial support, and only up to a certain point. But while it is being carried out, the body gets used to it pretty much, and subsequently cannot cope on its own.

Therefore, it is impossible to abruptly refuse Duphaston during pregnancy in any case. The scheme for starting and stopping the intake is calculated and prescribed by the doctor, based on the patient's tests and diagnosis.

In most cases, the daily dose is reduced daily by one tablet, then by half and a quarter. That is, taking the drug four tablets a day, on the second day of stopping treatment, the dose is three pills, on the third - two, on the fourth - one, on the fifth - half a pill, on the sixth and seventh a quarter.

This scheme is conditional, it must be adjusted and calculated by the attending physician. For many women, it takes several weeks to stop treatment. For problems with conceiving and bearing a child, Duphaston is taken on average for six months.

This period covers the time before, her initial terms (up to twelve weeks) and about fourteen days of gradual withdrawal of the drug. After the fifteenth week, a fully formed placenta begins to take care of the baby, the safety of the fetus ceases to depend on progesterone.

When planning a pregnancy and staying in this state for the first two trimesters, you should constantly monitor the level of progesterone. This control is carried out with the help of a blood test. During treatment with the drug, it is also recommended to undergo periodic examinations of the mammary glands, including mammography.

The cancellation of Duphaston, as well as its appointment, must be carefully weighed and justified. A big mistake of many women experiencing problems with conception is a sharp unauthorized termination of the drug immediately after the onset of pregnancy. This indiscretion is often very costly and ends in spontaneous miscarriage.

Today it is extremely difficult to find a woman who, directly during her own pregnancy or during the period when she was just planning one, would not use any medicines that are useful for the expectant mother herself and completely safe for her unborn baby. After all, on the one hand, such foresight gives a woman an excellent opportunity to give birth to her long-awaited baby quite healthy. On the other hand, it allows you to maintain your own health. Recently, such a diagnosis as habitual miscarriage has become a very common problem for women who really want to have their own children. There are truly an unusually many reasons for this, but one of the most important such reasons is the problems that a woman has at the hormonal level of her body.

As many already know, a strictly special hormone is “responsible” for the entire pregnancy, it is also called the pregnancy hormone - this is progesterone. As a rule, its main function is indispensable in the female body, which is preparing for possible cardinal changes - namely, to bear a baby. After all, firstly, progesterone usually helps the fetal egg to attach to the walls of the uterus in a timely and reliable manner, and it is he who prepares the female mammary glands for further production of both colostrum and milk. And secondly, thanks to just such a hormone as progesterone, the uterus is constantly quite actively growing and increasing in size, while practically not shrinking at all, which, of course, is extremely necessary just so that the female body can accept the embryo that it perceives as "foreign body", and did not reject it.

And as you understand, as soon as another pregnancy occurs, the total amount of progesterone in the body increases dramatically. But, unfortunately, this, alas, does not always happen, because we described a variant of the accepted norm. There are a number of specific reasons why the very necessary pregnancy hormone for a woman may not be produced in sufficient quantities. And it is quite understandable that without such a hormone, the uterus that is implanted in it may simply not accept the fetus (a spontaneous miscarriage will occur), and sometimes pregnancy may simply not occur at all.

And we tell you about all this, not in vain. Probably, you yourself have already guessed that in this article we will further discuss such a drug as the so-called synthetic analogue of this very necessary female progesterone for pregnancy. As a rule, this drug is prescribed only when it has been accurately confirmed in a particular woman (of course, only after passing all the necessary tests for the production of hormones by the body). By the way, it would be desirable to donate blood for the hormones produced by the body several times, and better in a row (this is necessary in order to determine your specific hormonal picture as accurately as possible), and always strictly on an empty stomach. The results of such analyzes will have to be deciphered only by your attending physician, and then he may consider it necessary to prescribe you some additional studies. And only after that the doctor will allow himself to prescribe certain medicines for a particular woman.

Why is Duphaston usually prescribed?

Yes, first of all, because our modern pharmaceutical market is able to offer us only two similar drugs from real-life progesterone analogues - this is the same Duphaston and the second drug called. Such a drug as Duphaston, although it is still the same progesterone of only synthetic origin, nevertheless it is more convenient for a woman to use it, at least unlike the same Utrozhestan. After all, Utrozhestan is progesterone, but already of natural origin, which doctors should only administer strictly intramuscularly. And as mentioned earlier, (say, with such a diagnosis as habitual non-carrying of a pregnancy), so actually during a pregnancy that has already begun, but which has real risks of interrupting it. Also, the drug Utrozhestan is also prescribed when planning a pregnancy - read more about this.

The correct dosage, and indeed the full course of treatment, should always be developed strictly individually, and depending on the available test results. Most often, they try to prescribe Duphaston in a dosage of 2 or a maximum of 3 tablets once or even twice a day. The full course of treatment with this drug is usually up to 6 months directly during the planning and preparation for pregnancy, and already with the onset of pregnancy, Duphaston should be taken only in the very first weeks of pregnancy, moreover, according to the same instructions, but constantly gradually reducing the intake the number of tablets, up to the complete abolition of those.

Also, such a drug as Duphaston may well be prescribed if it occurs, which most often happens in the early stages of pregnancy due to acute progesterone deficiency. And, as a rule, in this case, this drug is taken only up to 20 weeks of pregnancy, until the placenta can finally form in the woman’s body (after all, it has long been known that the already “ready” or ripe placenta significantly increases the production of the body itself, which is natural progesterone , and as a result, the fetus becomes protected from rejection by the mother's body).

Incredibly many questions in previously ill women can be caused by the process of canceling a drug such as Duphaston against the background of pregnancy. And, of course, on numerous forums, future and already established mothers actively share their experience, which, by the way, is very, very different. Many of the women Duphaston was canceled literally immediately at the first sign of pregnancy, but, unfortunately, the abrupt cancellation of this particular drug can be very dangerous for the fetus. After all, Duphaston supports a newly pregnant body with an additional, so necessary dose of the pregnancy hormone progesterone, and if suddenly such a supply of hormones is stopped too abruptly, then the woman’s uterus will be able to reject the fetal egg itself as a foreign body. And that is why a drug such as Duphaston will need to be canceled only gradually, moreover, from time to time it will be necessary to take tests for the production of hormones in order to strictly control the total amount of progesterone in the female body.

How exactly can Duphaston be canceled?

Unfortunately, in this question, as well as in many others, there is no clear and unambiguous answer among physicians. And the same reviews of "experienced" mothers are very different from each other. But modern doctors on this occasion can be unambiguous in only one thing. Namely, that the regimen for the abolition of Duphaston will have to be determined only by an experienced doctor, who, in fact, initially prescribed the regimen for taking the drug. After all, it is shown that Duphaston happens to women for completely different reasons, which is precisely why, and this drug will need to be canceled accordingly.

If you, for example, took this drug, exactly 4 tablets a day, and subsequently the results of the relevant tests showed that the total amount of progesterone is now normal, then this drug may be canceled as follows. On the first day you will have to drink - the prescribed four tablets, on the second day we drink - only 3 tablets, on the third day - 2 tablets, respectively, on the fourth day - you guessed it 1 tablet, and only after that is it possible to completely stop taking such a drug as Duphaston. If the total amount of progesterone in a woman’s body is somewhat deviated from the existing norms, then, of course, you will need a completely different scheme for drug withdrawal, which the doctor will have to determine based on the indicators of deviations from the norm that he saw in the tests. Sometimes pregnant women "stop taking" Duphaston on their own, and sometimes they do this for even a few weeks, which is also not entirely true.

And finally, let's talk about the so-called "pitfalls" possible when taking and canceling Duphaston. So, in the instructions for this drug (and actually from the lips of the vast majority of the most experienced and respected gynecologists) it is written in black and white that this drug can be absolutely safe, and can not harm either the expectant mother or, of course, her child. Rather, on the contrary, this drug is only very useful and even vital for almost every woman. However, it should be noted that some experts are extremely outraged by such information in the manufacturer's instructions. Indeed, in our days, and so Duphaston and the onset of pregnancy have become almost synonymous with words. And such a fairly serious drug is prescribed, as they say right and left, and sometimes without any serious reason, rather, just in case, calming oneself - because it will not hurt. But is it really so - the big question?

It is incredibly difficult to talk about this, so we bring to your attention only some of the statements of quite authoritative experts. It turns out that in many civilized countries of the world, taking such a drug as Duphaston during pregnancy is considered to be extremely undesirable and even harmful. No matter how you twist it, and whatever you say, it is hormonal and means a rather serious drug that may well upset your natural hormonal balance in the body in some way. And some of the experts generally believe that such a reception of Duphaston can “slow down” the normal natural production of progesterone by an already pregnant body. Actually, that is why if you have already taken this drug before pregnancy, then during the onset of pregnancy, it is absolutely impossible to abruptly cancel it, of course. Since your already pregnant body may not be able to independently cope with the need to produce such an important and even vital hormone, for the simple reason that the body has already been “accustomed” to receiving this hormone from the outside. And if in the early stages of pregnancy the level of progesterone in your body drops sharply, then it will be extremely difficult for you to avoid a spontaneous miscarriage.

And in order not to face such a dilemma (should Duphaston be canceled during pregnancy or not, and if so, how?), it would be necessary to never take it at all. The last of modern studies have shown and proved that in fact, only a few women can really need such an “artificially derived” progesterone, and this drug is prescribed by almost every second of all pregnant women.

Such an "ambiguous" attitude to drugs in our time is, unfortunately, quite a common thing. And how truly difficult it is for a pregnant woman to make the right choice in such a situation, when the information constantly coming to her is so contradictory and confusing. What should you do if, for example, one doctor insists that it is necessary and important to use this drug, and the second convinces that it is definitely not worth it?

The final choice, unfortunately, as always, falls only on the fragile shoulders of a pregnant woman ... and so much I want not to be mistaken in this matter.

Believe in your own strength, listen to your body and everything will be fine with you, of course!

Of course, one of the main purpose of any woman is motherhood. It is the birth of a baby that is a great happiness for every family.

However, there are situations when a woman cannot get pregnant or bear a healthy baby. It is good that at such moments modern medicine allows you to eliminate a large number of obstacles to successful fertilization and future childbirth.

If a woman has a hormonal failure, which is the main cause of infertility, miscarriages and other pathologies, then they come to the rescue. To solve these problems, the hormonal remedy Duphaston has earned a good reputation.

What is Duphaston?

Duphaston (Duphaston)- This is a medicine in tablets used to treat diseases of the female reproductive system. For women, it is completely safe. The drug has practically no side effects on the body.

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This medication is hormonal, and you can drink it only as directed by your doctor, after conducting a lot of examinations and various tests on the hormonal background of the body. The doctor will create an individual card, tell you how to use the medication, indicating the doses and duration of administration, and also tell you how to properly finish the use of Duphaston.

Unauthorized use or cancellation of the use of such a medicine is strictly prohibited - this can provoke unpredictable complications.

The active substance is dydrogesterone, a hormone synthesized by an artificial method, which is an analogue of progesterone that is generated in the human body. The natural hormone is often referred to as the “pregnancy” hormone due to the fact that it is he who oversees the reproductive function in the female body.

Thanks to dydrogesterone, which is obtained artificially, it was possible to eliminate almost all the side effects of natural hormonal drugs, for example:

• blood clotting imbalance;
• glucocorticoid action;
• plastic metabolism (anabolic action);
• estrogen activity;
• activity of thermogenics;
• androgenic effect

Duphaston received a lot of positive feedback from doctors and patients.

Instructions for use Duphaston

It is necessary to use Duphaston during pregnancy only as directed by a specialist who will determine an individual regimen for admission.

Rules for taking Duphaston

When taking Duphaston tablets, you must adhere to the following general rules:

1. The drug must be used at regular intervals. Norma, if you take a pill at 7 o'clock in the morning, then the next time you need to drink it at 7 o'clock in the evening.
2. If you miss a tablet, it is necessary to wait for the next reception time so as not to violate the frequency.
3. It is necessary to stop taking Duphaston after being convinced that pregnancy has not occurred. To do this, you can take a pregnancy test or blood for hCG, if there is a delay in menstruation.
4. In case of pregnancy, it is strictly forbidden to stop drinking it. It is necessary to contact your doctor if the patient drank Duphaston.
5. Cancellation of Duphaston is carried out in stages, according to the plan chosen by the attending gynecologist.

What are they prescribed for?

Duphaston is prescribed to women during maintenance or replacement therapy, when a lack of progesterone is detected, on which conception, gestation, and childbirth itself directly depend. Relaxation of the uterus and its premature contraction are important effects of progesterone

The lack of a sufficient amount of this hormone at the stage of pregnancy can lead to the following consequences:

With the above ailments and dysfunctions, experts often prescribe Duphaston.

Prescribing a medication when planning conception

With the help of the hormonal drug Duphaston, a favorable background is created in the female body for the fertilization of the egg, the introduction of the embryo into the uterus and the subsequent development of the fetus.

When planning the conception of a child, these pills should again be prescribed by a specialist, since there is no universal scenario for taking them.

Basically, for the conception of a child, the drug is prescribed to be taken on the next day after ovulation and taken until the onset of menstruation. It is recommended to cancel the drug only when taking the test or at the initial stage of menstruation to make sure that there is no pregnancy.

The fact is that a sharp decrease in progesterone in the blood can worsen the nutrition of the embryo or its complete rejection. Taking this medication at the stage of planning a child with a detected hormonal imbalance, Duphaston has a greater effect in the future during pregnancy.

The full effect of taking Dufaston to conceive a fetus occurs after 6 months. When the drug is taken for more than a year without results, it is recommended to contact your doctor to change the tactics of treatment, further examinations or prescribing other drugs, to find an effective substitute for the drug.

Refuse to take this medication, in cases of its appointment for prophylaxis without additional examinations. Find another gynecologist!

Duphaston in early pregnancy

At the first stage of pregnancy, Dufaston tablets are used when insufficient is generated in the ovaries of a woman.

This medication has a selective effect on the endometrium, thereby maintaining it in the state necessary for the development of the embryo, and also keeps contractions of the smooth muscles of the uterus, thereby preventing possible miscarriage.

Thus, this drug can fully replace the natural hormone at an early stage of pregnancy.

The drug does not have a negative reaction to the fetus and the mother's body during this period of pregnancy. It is usually prescribed in the first and second trimester of pregnancy to preserve it.

As soon as the signs of miscarriage have disappeared, it is worth taking the drug in the same doses for about a week, and then switching to a lower dose to maintain hormone levels. It is strictly forbidden to abruptly stop taking the medication, as this can lead to termination of pregnancy.

Prescribing the drug during pregnancy

At later stages of pregnancy, namely from the third trimester of fetal maturation, the drug should be used with caution, because at these times it can cause liver dysfunction.

At this stage, Duphaston tablets cope with the following tasks:

Also during pregnancy, the medication can be prescribed for endometritis in the chronic stage.

A distinctive feature of this disease is the increased militancy of the immune system, which considers the embryo as a foreign body and tries to quickly remove it from the female body.

This medication blocks this factor, bringing the immune system back to normal, thereby eliminating the possibility of a miscarriage.

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The disadvantage of most drugs are side effects. Often, drugs cause severe intoxication, subsequently causing complications in the functioning of the kidneys and liver. To prevent the side effects of such drugs, we want to pay attention to special phytotampons.

Treatment for endometriosis

It is known that one of the main causes of endometriosis is an increased level of estrogen in a woman's body. As a result, it is worth using Duphaston, which, with endometriosis, lowers the level of estrogen and stabilizes the cumulative level of hormones.

The following characteristic features of the use of the drug for the treatment of this disease can be distinguished:

1. Dydrogesterone mainly for the most part has an effect on the uterine mucosa, inhibiting the growth of endometrial receptors.
2. Since the menstrual period is not in a depressing stage, the likelihood of conceiving a child remains.
3. Duphaston reduces the tone and contractility of the smooth muscles of the uterus, which in the early stages of pregnancy reduces the risk of spontaneous abortion.
4. Thanks to this drug, the pain syndrome decreases or disappears without a trace. This is due to the fact that there is a decrease in the generation of prostaglandins, which in turn cause a sharp narrowing and compression of the vessels of the circulatory system.
5. Duphaston significantly reduces the risk of degeneration of cells with pathology into cancerous neoplasms. According to numerous reviews of patients who took Duphaston, the menstrual cycle is tolerated more calmly and with less pain, it stops pulling the lower abdomen.

How to use hormonal pills for endometriosis, it is imperative to specify with the attending specialist, but, by and large, the instruction looks like this:

1. Dufaston is taken twice a day, at the same time of day. For example, at 8 am and 8 pm.
2. The duration of admission is individual in each case, but usually ranges from 5-6 to 20 days.
3. Sometimes the drug is taken for a long time without interruption from 6 to 9 months, which allows the disease to atrophy (regression).

As with other reasons for taking Duphaston, with endometriosis it should also be used according to the recommendations of the attending specialist, and not self-medicate.

Infertility and Duphaston

• When a woman is childless, which is determined by the luteal insufficiency of the phase of the menstrual cycle, Duphaston is taken from 14 to 25 days of the cycle. The minimum duration of drug use is 6 months, after which it is necessary to stop taking the drug. After the onset of pregnancy, the drug is used for about 16-20 weeks, then you need to stop taking the drug.
• With hormonal disorders
• Dufaston can be used to diagnose secondary amenorrhea and dysfunctional uterine bleeding. In case of hormonal failures, carry out replacement therapy in women with disorders caused by menopause with an intact uterus.

Stories from our readers!
“The gynecologist advised me to take natural remedies. We opted for one drug - which helped to cope with hot flashes. It’s such a nightmare that sometimes you don’t even want to leave the house for work, but you have to ... As soon as I started taking it, it became much easier, you even feel that some kind of internal energy appeared. And I even wanted to have sexual relations with my husband again, otherwise everything was without much desire. "

How to choose the right dosage?

When dosing the drug Duphaston, you must adhere to the following rules:

1. With PMS- 10 mg of the drug twice a day from the 12th to the 28th day of the cycle.
2. For menstrual disorders- 10 mg of the drug twice a day from 11 to 25 days of the cycle. Treatment continues for at least 6 cycles.
3. With endometriosis- the daily dose of the drug can vary from 10 to 30 mg from the 5th to the 25th day of the cycle or taking it on an ongoing basis.
4. With infertility- apply the medicine twice a day, 5 mg from the 14th to the 25th day of the cycle. The duration of therapy should not be less than 6 cycles.
5. With a threatened miscarriage- take 20 mg of the drug immediately, and then reduce the intake to 10 mg twice a day (morning and evening at equal hours). If the threat of miscarriage persists, Duphaston can be taken 5 mg three times a day (every 8 hours). When the symptoms of a miscarriage have disappeared, the drug is still taken for about a week. In case of recurrence of symptoms, the drug should be immediately used in the dosage that had the greatest effect on their elimination.
6. For habitual miscarriage: the daily dose of 10 mg is divided into 2 doses. The duration of the course can be up to 20 weeks. After the disappearance of the symptoms of a miscarriage, Duphaston is gradually canceled.

To whom is Duphaston contraindicated?

There is no fatal contraindication of the active substance Duphaston in patients with chronic renal failure.

My personal history

With premenstrual pain and unpleasant discharge, it's over!

Our reader Egorova M.A. shared experience:

It is scary when women do not know the true cause of their illnesses, because problems with the menstrual cycle can be harbingers of serious gynecological diseases!

The norm is a cycle lasting 21-35 days (usually 28 days), accompanied by menstruation lasting 3-7 days with moderate blood loss without clots. Alas, the state of gynecological health of our women is simply catastrophic, every second woman has some kind of problem.

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Side effects of Duphaston

When using the drug, some side effects may occur:

• very rarely, hypersensitivity of the immune system may appear;
• single precedents of hemolytic anemia were recorded;
• the appearance of headaches and migraines;
• liver dysfunction may begin, expressed by jaundice, pain in the abdomen and general weakness of the body;
• Quincke's edema was extremely rarely recorded;
• a rare manifestation of subcutaneous tissue, urticaria and skin irritation;
• it is possible to increase the sensitivity of the mammary glands;
• rarely, when taking, breakthrough bleeding in the reproductive system is likely to occur, which disappear after increasing the dose of the drug;
• extremely rarely, peripheral edema appears (the appearance of excess fluid in the tissues and cavities of the body);
• possible general disorders of the body.

If you notice any of the listed side effects, you should immediately contact your doctor to find out if you can stop or continue taking the drug.

Duphaston and alcohol

The manufacturer of the drug in the instructions for the drug indicated its possible negative effect on the liver. Since alcohol also has a negative effect on the liver, taking any medication increases the load on this organ.

The interaction of Dufaston with alcohol, which can have a negative effect on the liver, is a triple load.

Among other things, alcohol changes the enzyme composition of the liver, which can lead to improper effects of this drug.

The reaction to the gastrointestinal tract, if you combine duphaston and alcohol, is also ambiguous.

The active substance of the drug relaxes the abdominal muscle group, and alcohol is a poison that the human body tries to quickly remove.

Adding these two factors, taking the drug and alcohol can lead to vomiting or diarrhea, which means the rapid removal of the active substance of the drug from the body, and this will reduce the entire positive effect of its use to a minimum, and there is simply no point in taking it.

Any kind of alcohol when prescribing a medication to preserve the fetus is strictly contraindicated. Even in the absence of medication to maintain pregnancy, it is forbidden to drink alcohol.

Alcohol also has an effect on blood vessels, they either narrow or expand. This negatively affects the hemodynamics of the organs of the reproductive system, which contributes to hormonal disorders.

With the above negative factors, the compatibility of alcohol and Dufaston, we can conclude why drink alcohol if it greatly reduces the effectiveness of this medication.

However, if alcohol cannot be avoided, then you should limit yourself to one glass of good wine, adding ice or water to it. At least 2 hours should elapse from drinking alcohol to taking the medicine.

Duphaston or Utrozhestan?

Utrozhestan is made from the natural hormone progesterone from herbal ingredients.

The resulting substance is almost completely similar to the natural hormone that is produced by the woman's placenta. Thanks to this, the body perfectly assimilates it as compatible, taking it as true.

Indications for taking Utrozhestan are:

• infertility, which is caused by hormonal imbalance;
• risk of miscarriage;
• hyperandrogenism (increased content of the male sex hormone in the blood) and other pathologies that arose against the background of hormonal failure.

Neither Utrozhestan nor Dufaston inhibit ovulation when taken at the prescribed dosage for therapeutic purposes in the second phase of menstruation. The abolition of both drugs is carried out gradually, reducing the dose by the date prescribed by the gynecologist. Both drugs also do not have a negative effect on the mother and child if they are taken as prescribed by the doctor.

Pros and cons of Duphaston and Utrozhestan

Sometimes women, when faced with the need to take hormonal drugs, using the example of Duphaston and Utrozhestan, ask themselves if they can differ? Is it possible to replace the drug?

These two drugs at first glance are very similar, but there is a difference. Can I replace the drug? Is it possible to take both drugs at the same time?

Comparing these preparations by composition, one can distinguish the difference in the method of production of the active substance:

• Utrozhestan is made from progesterone of plant origin;
• Duphaston is made from a synthesized hormone.

Duphaston has a smaller number of detrimental effects characteristic of Utrozhestan:

• frequent dizziness;
• drowsiness (Utrozhestan has a calming effect);
• weakness;
• changes in body weight;
• nauseating effect.

However, Utrozhestan has two methods of application. The drug can be used orally (with a liquid) and intravaginally (into the vagina) methods.

Duphaston also does not affect the following points:

1. The ability to drive a motor vehicle (driving while taking Utrozhestan is recommended to be carried out with caution).
2. Basal temperature indicators (sufficient doses of Utrozhestan lead to a sharp increase in basal temperature)

Which medication to choose - Utrozhestan or Duphaston - for conceiving a child or during pregnancy, is determined purely individually. Sometimes gynecologists prescribe the patient the simultaneous administration of two drugs at once.

Terms of sale

Implementation in pharmacies is carried out only according to a prescription written in Latin.

Prices for Dufaston

The cost of the drug varies 400-500 rubles per package . The price of tablets in different cities of Russia will depend on the place of sale, ongoing promotions and discounts in pharmacy organizations. For example, in the Ozerki pharmacy, pills cost about 450 rubles per package.

Release form

Duphaston is available in tablet form for oral administration. Tablets weighing 10 mg coated with excipients.

Storage conditions

Store tablets in a dry place at a temperature not exceeding 30 degrees.

Best before date

The shelf life of the drug is about 5 years, after which it is forbidden to take it.

Pregnancy is a very important and responsible stage in the life of every woman. During pregnancy, the abolition of Duphaston should also take place under the supervision of a doctor and with mandatory monitoring of the level of progesterone in the body. Women's reproductive health is very sensitive to the impact of negative factors of the external and internal environment. In this regard, chronic stress, physical and mental strain, dietary errors and bad habits can lead to disruptions in a woman's hormonal system.

Hormonal regulation is responsible for the successful course of pregnancy. Quite often, women have a deficiency of the hormone progesterone, and doctors prescribe hormone replacement therapy with Duphaston. Before starting treatment, the doctor should explain how to take the drug correctly, and how Duphaston is canceled. It is important to remember that self-cessation of treatment can lead to serious consequences for the health of the expectant mother and fetus.

Why is the drug prescribed to pregnant women

To understand how to cancel Duphaston during pregnancy, you need to know why doctors prescribe this drug, and how it affects the body of a pregnant woman. The composition of the drug includes dydrogesterone, which is a synthetic analogue of an important regulator of pregnancy - the hormone progesterone. This hormone is responsible for the timely preparation of the walls of the uterus for the attachment of the fetal egg to them. If the body of the expectant mother has an insufficient level of progesterone, then the embryo will not be able to penetrate into the mucous membrane and a spontaneous abortion will occur.

There are clear indications for the appointment of Duphaston:

• habitual miscarriage (a woman has several miscarriages in history);
• dysmenorrhea;
• endometriosis;
• risk of miscarriage.

Before the appointment of Duphaston, the gynecologist necessarily conducts a comprehensive examination of the woman's body. If a woman cannot become pregnant for a long time or several previous pregnancies ended in spontaneous abortions, then treatment should be carried out for 3-6 cycles before the intended conception. Duphaston is also used in women with signs of miscarriage in early pregnancy.

It is necessary to drink tablets according to special schemes that your doctor can adjust depending on the specific clinical situation.

The main characteristics of the drug

Duphaston is available in tablet form and is well absorbed in the gastrointestinal tract. This form of release is very convenient for pregnant women. One tablet contains 10 mg of dydrogesterone. This synthetic substance, unlike natural progesterone, does not cause such side effects as:

• headache;
• weakness, sleep disturbance;
• nausea;
• sudden mood swings.

Duphaston does not have a masculinizing effect (there is no coarsening of the voice, excessive hair on the body and face), does not affect the weight and amount of body fat. This hormonal drug is effective and safe for both the woman and the fetus. However, during pregnancy, the drug should be discontinued with great care and only under the supervision of the attending physician. Sudden withdrawal of the drug can lead to unpleasant consequences for the health of the woman and the fetus.

How to cancel the drug

The Dufaston withdrawal scheme is determined individually for each individual woman and depends primarily on the level of progesterone in the body, as well as on the indications for prescribing the drug. To deal with the abolition of this hormonal drug should be a qualified specialist with experience in managing patients taking Duphaston.

Stop taking the drug should be in the case when the level of progesterone in the body returned to normal or the woman had unwanted adverse reactions to the drug. It is necessary to start the cancellation gradually, slightly reducing the dosage of the drug. As a rule, the reason for canceling Duphaston during pregnancy is the 20th week. If you took 4 tablets a day, then every day their number should be reduced by one, therefore, the drug withdrawal takes about 4 days.

The time of withdrawal of the drug may vary depending on the condition of the pregnant woman and the initial dosage of Duphaston. Given the large number of factors that affect the process of stopping therapy, it is not possible to unambiguously answer the question of how to cancel Duphaston. In order not to risk your health and the health of your unborn baby, it is better to consult a specialist whom you can completely trust.

Abrupt discontinuation of Duphaston is considered dangerous and can lead to serious complications.

The consequences of drug withdrawal during pregnancy may be bleeding from the genital tract and spontaneous abortion.

These pathological conditions occur due to a sharp decrease in the amount of progesterone in the body. Receiving the hormone from the outside, the endocrine system stops producing progesterone in the right quantities, and the abrupt withdrawal of the drug will lead to a deficiency of this hormone in the blood. Therefore, stop treatment, you need to strictly follow all the recommendations of your doctor.

Not all women can easily get pregnant once they have made the decision to have a baby. Many are facing problems. And, if these problems are minor, for example, hormonal failure, they can be solved using special preparations for this. One of the drugs that are used in planning to restore hormonal balance, increase progesterone levels, is Duphaston. We will disclose the instructions for use when planning a pregnancy of this drug in this article.

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Although, this drug is sometimes prescribed to those women whose hormonal levels are normal, for example, when a woman is over 30 years old. The reason for this is a decrease in the chances of getting pregnant, and if a woman is planning a pregnancy, but she does not succeed, or problems with bearing, Duphaston helps to solve this problem. The drug helps to normalize the work of the secret glands of the uterus, which increases the chances of the embryo to attach to the wall of the uterus.

The package contains 20 tablets. Usually, the remedy is taken from the 11th to the 26th day of the cycle. But, the exact dosage regimen and dosage will be reported by the attending physician, after a complete medical examination. If no other serious disruptions were found in the body, except for hormonal disorders, then the problem will soon be solved, and two cherished strips can be seen on the test.

In no case should this drug be taken just like that, both when planning a pregnancy, and after its onset. The doctor also cannot prescribe it without evidence. First, the woman passes the necessary tests. And only according to their results, the doctor determines the dosage, the duration of the course.

Duphaston has many analogues, it is also produced in candles, but without consultation they do not replace the original drug.

Duphaston continues to be taken during early pregnancy. In no case, if this drug was taken during pregnancy planning, it should not be abruptly abandoned. Having discovered her interesting position, a woman should inform her gynecologist about this. He will order additional tests, ultrasound, to confirm the pregnancy and make sure everything is in order and there are no problems. Then, the doctor simply adjusts the dosage of the drug, but does not cancel it immediately.

Duphaston helps to “fix” the pregnancy, and in a certain dosage does not affect the development of the fetus, the main thing is to follow the instructions and not engage in amateur activities.

Until what week of pregnancy to take the drug?

Usually, take it until the 20th week of pregnancy. But, it is not canceled immediately, but gradually reducing the dosage so that there is no stress for the body, and a miscarriage does not occur. Abrupt cancellation is fraught with a sharp decline in hormonal function, which can provoke irreversible consequences, in the form of spontaneous abortion.

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Dosage reduction and cancellation of Duphaston - scheme

As mentioned above, it is necessary to cancel the drug not immediately, but gradually. The withdrawal plan is prescribed by the doctor. Depending on the dosage and number of doses per day. For example, if a woman took 3 tablets a day, when canceled, she already takes 2 tablets a day for the next week, and 1 tablet a day for the next week. In some cases, the doctor may prescribe an additional week of admission. Usually, in such cases, half a tablet per day is already taken. If, upon cancellation, there is a threat of miscarriage, the course of taking the drug can be repeated.

Reviews about Duphaston when planning pregnancy

Women who have undergone treatment with it leave their opinion on the drug on the forum. Reviews about Dufaston, who took it when planning a pregnancy for women, are often positive, but there are also neutral ones:

Madina, 31 years old, Nartkala

Motherhood turned out to be a cherished dream for me, because I was diagnosed with infertility. Since I am from the Caucasus, it was also a stigma. Therefore, I waited for my husband’s relatives to persuade him to send me such a useless “non-woman” home and get a divorce. But, the husband turned out to be more humane, saying that this is not a hindrance, and that he loves me. And I continued, but already without enthusiasm, to look for good doctors so that they would still help me. I didn’t find it, I spat on everything and already got used to the fact that in old age a glass of water, at best, will be given to us by a cat. Then, somehow I went for a routine examination at my clinic. There was a new gynecologist. Or rather, not a new one, she just came out of the decree, and I had not seen her before. She then decided to start all over again, looking at my anamnesis. To be honest, I didn’t want to take everything in a new circle, but new details surfaced. Progesterone was almost at zero, with a thyroid problem. She said that even if I don’t get pregnant myself, I can try IVF. Why didn't others tell me this? To restore the hormonal balance, I was prescribed Duphaston, a course for 3 months, but after the 3rd I could not get to the doctor, and drank another 1 month. I took a pregnancy test after each pack. I. BINGO! After the 4th package, I saw the cherished 2 strips. Stunned! Pregnancy was oh, how not easy, almost the entire 9 months lay in storage, but I gave birth to her - my daughter! Thanks to Duphaston and this wonderful doctor!

Elizaveta T, 28 years old, Kaliningrad

For 8 long years I tried to become a mother. And almost every time a new doctor prescribed me Duphaston. But it didn't help me get pregnant. The long-awaited pregnancy came after a course of taking other drugs. Duphaston was prescribed to me again to keep the pregnancy in the early stages. To make up for my progesterone deficiency. The pregnancy was saved. My daughter was born on time and completely healthy. Then, he was assigned to me. To normalize the cycle because it has gone astray. Helped. I can not recommend or not recommend this drug and speak unambiguously. What does it help or not. It did not help to get pregnant, but yes, to save the child.

Alexandra. 21 years old, Novosibirsk

My husband and I really wanted Lyalka, but it didn’t work out. It turned out that I had grade 4 endometriosis, which practically equated my chances of getting pregnant to zero. Duphaston was prescribed to increase the amount of progesterone. I drank 4 tablets a day every 6 hours for 2 months. Didn't get pregnant. Then, after the abolition of this drug, I vomited after the berry jelly. I thought that the gastritis woke up, but no. The test showed pregnancy!

Why does a woman's body need progesterone, in detail in the video: